Table 3.
Sensitivity, specificity, optimal cutoff point, and Area Under ROC Curve (AUC) of tests
| Youden index | Sensitivity (%) | Specificity (%) | Optimal cut-off point | AUC | |
|---|---|---|---|---|---|
| MMSE score | 0.655 | 83.8 | 81.7 | ≤28 | 0.891 |
| MoCA total score | 0.853 | 97.8 | 87.5 | ≤23 | 0.965 |
| MoCA delayed recall score | 0.612 | 77.9 | 83.3 | ≤3 | 0.830 |
| ACE-III total score | 0.887 | 91.2 | 97.5 | ≤85 | 0.980 |
| ACE-III orientation/attention score | 0.420 | 66.2 | 24.2 | ≤18 | 0.752 |
| ACE-III memory score | 0.505 | 77.2 | 73.1 | ≤24 | 0.844 |
| ACE-III language score | 0.588 | 84.6 | 74.2 | ≤22 | 0.876 |
| ACE-III verbal fluency score | 0.471 | 52.9 | 94.2 | ≤11 | 0.824 |
| ACE-III visuospatial score | 0.532 | 82.4 | 70.8 | ≤15 | 0.826 |
Abbreviations: ACE-III, Addenbrooke’s Cognitive Examination III; MoCA, Montreal Cognitive Assessment; MMSE, mini-mental state examination.