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. 2019 Sep 13;11:8345–8358. doi: 10.2147/CMAR.S210029

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© 2019 Wawruszak et al.

This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).

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mRNA expression of CDH1 (E-cadherin) and CDH2 (N-cadherin) in breast cancer cell lines after VPA or SAHA treatment.

Notes: Expression of CDH1 (A) and CDH2 (B) was analyzed by qPCR in T47D, MCF7, MDA-MB-231, MDA-MB-468 and BT-549 cells exposed to either culture medium alone (control) and VPA (2 mM, 5 mM) or SAHA (2 µM, 5µM) for 24 hrs. The differences between groups were evaluated using the one-way ANOVA; Tukey’s post-hoc test. p<0.05 was considered to indicate a statistically significant difference. Results were presented as mean ± SD.

Abbreviations: SAHA, vorinostat; VPA, valproic acid.