Table 3.
Distribution of comorbidities in patients with tinnitus and their matched controls: otological and vestibular disorders
| Tinnitus cases (%) | Tinnitus-free controls (%) | OR crude (95% CI) |
OR adjusteda (95% CI) |
|
|---|---|---|---|---|
| Sensorineural Hearing Loss | ||||
| ≤30 days prior to (includigng) the ID | 618 (0.6) | < 5b (0.0) | 156.99 (58.81–419.08) | 161.70 (60.56–431.73) |
| 31 to 360 days prior to the ID | 179 (0.2) | 60 (0.1) | 3.18 (2.36–4.28) | 3.10 (2.29–4.18) |
| >360 days prior to the ID | 1142 (1.0) | 701 (0.6) | 1.68 (1.53–1.85) | 1.68 (1.53–1.85) |
| Acute vestibular neuronitis | ||||
| ≤30 days prior to (includigng) the ID | 37 (0.0) | < 5b (0.0) | 36.15 (5.07–257.83) | 34.14 (4.79–243.60) |
| 31 to 360 days prior to the ID | 68 (0.1) | 27 (0.0) | 2.58 (1.64–4.05) | 2.37 (1.50–3.73) |
| >360 days prior to the ID | 390 (0.4) | 236 (0.2) | 1.66 (1.41–1.95) | 1.63 (1.39–1.92) |
| Otitis media | ||||
| ≤30 days prior to (includigng) the ID | 1114 (1.0) | 51 (0.1) | 22.91 (17.30–30.32) | 22.82 (17.23–30.22) |
| 31 to 360 days prior to the ID | 1753 (1.6) | 489 (0.5) | 3.82 (3.45–4.23) | 3.81 (3.44–4.22) |
| >360 days prior to the ID | 11,552 (10.5) | 9483 (8.6) | 1.33 (1.29–1.37) | 1.31 (1.27–1.36) |
| Labyrinthitis | ||||
| ≤30 days prior to (includigng) the ID | 408 (0.4) | 20 (0.0) | 20.90 (13.34–32.73) | 20.19 (12.88–31.65) |
| 31 to 360 days prior to the ID | 867 (0.8) | 277 (0.3) | 3.26 (2.85–3.74) | 3.19 (2.78–3.66) |
| >360 days prior to the ID | 4338 (4.0) | 3014 (2.8) | 1.49 (1.42–1.57) | 1.46 (1.40–1.54) |
| Conductive Hearing Loss | ||||
| ≤30 days prior to (includigng) the ID | 52 (0.1) | < 5b (0.0) | 17.32 (5.41–55.42) | 19.51 (6.07–62.74) |
| 31 to 360 days prior to the ID | 29 (0.0) | < 5b (0.0) | 7.25 (2.55–20.62) | 7.23 (2.53–20.67) |
| >360 days prior to the ID | 290 (0.3) | 229 (0.2) | 1.27 (1.07–1.51) | 1.25 (1.05–1.48) |
| Benign positional vertigo | ||||
| ≤30 days prior to (includigng) the ID | 462 (0.4) | 37 (0.0) | 13.11 (9.37–18.34) | 12.94 (9.24–18.11) |
| 31 to 360 days prior to the ID | 960 (0.9) | 398 (0.4) | 2.56 (2.28–2.89) | 2.48 (2.20–2.80) |
| >360 days prior to the ID | 3488 (3.2) | 2294 (2.1) | 1.60 (1.51–1.69) | 1.56 (1.48–1.65) |
| Cerumen | ||||
| ≤30 days prior to (includigng) the ID | 4249 (3.9) | 407 (0.4) | 11.74 (10.58–13.04) | 11.56 (10.41–12.83) |
| 31 to 360 days prior to the ID | 6680 (6.1) | 3512 (3.2) | 2.17 (2.07–2.26) | 2.12 (2.03–2.21) |
| >360 days prior to the ID | 14,702 (13.4) | 14,513 (13.2) | 1.13 (1.10–1.16) | 1.11 (1.08–1.14) |
| Otitis externa | ||||
| ≤30 days prior to (includigng) the ID | 1875 (1.7) | 203 (0.2) | 9.88 (8.54–11.44) | 9.87 (8.52–11.43) |
| 31 to 360 days prior to the ID | 3575 (3.3) | 1506 (1.4) | 2.55 (2.40–2.71) | 2.54 (2.39–2.70) |
| >360 days prior to the ID | 13,171 (12.0) | 11,085 (10.1) | 1.28 (1.24–1.31) | 1.26 (1.23–1.30) |
Notes: aAdjusted for BMI category, smoking status, alcohol consumption. bFor confidentiality reasons, we do not provide the number of patients in categories containing less than five patients.
Abbreviations: CI, confidence interval; ID, index date; NA, not available; OR, odds ratio.