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. 2019 Sep 13;11:8359–8370. doi: 10.2147/CMAR.S202631

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© 2019 Liu et al.

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UBE2T accelerates migration and invasion of hepatoma cell lines. (A) UBE2T knockdown significantly inhibited the migration ability, whereas UBE2T overexpression significantly enhanced the migration ability of hepatoma cells using Transwell assay (P<0.01; for 48 hrs after attachment). (B) UBE2T knockdown significantly inhibited invasion ability, whereas UBE2T overexpression significantly enhanced invasion ability of hepatoma cell lines using a Transwell assay (P<0.01; for 48 hrs after attachment). Data are presented as mean±SD. *P<0.05,**P<0.01 versus the control group.

Abbreviations: UBE2T, ubiquitin-conjugating enzyme E2T; UBE2T-KD, UBE2T knockdown; UBE2T-OE, UBE2T overexpression.