Figure 3.

The α6 integrin and E-cadherin distribute to a cell-cell location within invasive networks and cohesive clusters. The distribution of α6 integrin (red) and E-cadherin (green) in DU145 α6WT networks (A, B) or in DU145 α6AA cohesive clusters (C, D). The diagonal white lines on A, C are image lines from one side of the network (a) to the other side of the network (b), correspond to a distance of 200-300 microns and the pixel grey values are mapped (B, D). Results are representative of at least 3 independent experiments. Scale bars: 100 microns.