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. Author manuscript; available in PMC: 2020 Mar 15.
Published in final edited form as: Cancer Res. 2019 Jul 23;79(18):4703–4714. doi: 10.1158/0008-5472.CAN-19-0868

Figure 5.

Figure 5.

Cell-Cell biophysical properties are increased in cells expressing the uncleavable α6 integrin mutant. A. Cell-Cell ECIS resistance measurements at 400 Hz in DU145 α6WT, DU145 α6KO and DU145 α6AA cells in the absence (solid lines) or presence (broken lines) of 1uM S1P treatment given at 24 hours after seeding. B. Cell-ECM Coverage by ECIS resistance measurements at 40,000 Hz in DU145 α6WT DU145 α6KO and DU145 α6AA cells in the absence (solid lines) or presence (broken lines) of 1uM S1P treatment given at 24 hours after seeding. Results are representative of at least 3 independent experiments.