. Author manuscript; available in PMC: 2020 Sep 1.

Published in final edited form as: J Affect Disord. 2019 May 28;256:8–16. doi: 10.1016/j.jad.2019.05.055

Table 3.

Correlation of fractional anisotropy with percent change in HDRS.

Seed to target pair	Partial correlation coefficient	95% CI lower	95% CI upper	P-value
Raphe to left amygdala	0.18	0.01	0.33	0.04^*
Raphe to right amygdala	0.09	− 0.08	0.25	0.42
Raphe to left hippocampus	0.05	− 0.12	0.21	0.44
Raphe to right hippocampus	− 0.05	− 0.22	0.11	0.69

HDRS: Hamilton Depression Rating Scale, CI: confidence interval. P-values are from linear mixed model and are Bonferroni corrected for left and right amygdala. Partial correlation coeffcients were calculated from linear mixed model after adjusting for age, sex and study site.

p < 0.05.

(p=0.59 and 0.95 for tracts terminating in the left and right amygdala, respectively). Similarly, there was no significant treatment interaction in the relative change in HDRS score for left or right amygdala (p=0.27 and 0.91, respectively).