Appendix Table II.
Adjusted Odds Ratios (AOR) and 95% Confidence Intervals (CI) of Biological, Demographic, Socio-economic, Lifestyle/Behavioral, and Health Conditions from Logistic Regression on Alzheimer’s Diseases and Related Dementias in adults ≥65 years, Medical Expenditure Panel Survey, 2009e2015
| AOR | 95%CI | Significance | |
|---|---|---|---|
| Biological Factors | |||
| Sex | |||
| Male (ref) | |||
| Female | 0.89 | [0.68, 1.16] | 0.3903 |
| Race | |||
| White Non-Hispanic (ref) | |||
| African American | 1.56 | [1.15, 2.11] | 0.0045 |
| Hispanic | 0.66 | [0.43, 1.00] | 0.0498 |
| Other-race | 1.21 | [0.75, 1.96] | 0.4280 |
| Age | |||
| 65–69 Years (ref) | |||
| 70–74 Years | 2.97 | [1.87, 4.70] | 0.0001 |
| 75–79 Years | 4.12 | [2.58, 6.58] | 0.0001 |
| GE 80 years | 10.9 | [6.92, 17.17] | 0.0001 |
| Demographic and Socio-Economic status | |||
| Marital Status | |||
| Married (ref) | |||
| Widowed | 1.00 | [0.76, 1.31] | 0.9728 |
| Separated/Divorced | 1.19 | [0.82, 1.72] | 0.3707 |
| Never married | 0.77 | [0.42, 1.43] | 0.4102 |
| Poverty Status | |||
| High Income (ref) | |||
| Poor | 0.68 | [0.50, 0.93] | 0.0167 |
| Low Income | 0.83 | [0.63, 1.09] | 0.1882 |
| Middle Income | 0.91 | [0.69, 1.21] | 0.5137 |
| Education (in years) | |||
| >12 years (ref) | |||
| <12 years | 1.64 | [1.17, 2.31] | 0.0043 |
| 12 years/GED | 1.34 | [1.00, 1.78] | 0.0481 |
| Behavioral/Lifestyle Factors | |||
| Obesity | |||
| Underweight/Normal (ref) | |||
| Over weight | 0.86 | [0.69, 1.07] | 0.1704 |
| Obese | 0.52 | [0.37, 0.74] | 0.0003 |
| Current Smoking | |||
| Other (ref) | |||
| Current smoker [Continued] | 0.96 | [0.65, 1.43] | 0.8402 |
| Exercise* | |||
| Yes (ref) | |||
| No | 2.36 | [1.80, 3.10] | 0.0001 |
| Treatment Factor | |||
| Polypharmacy | |||
| <6 prescription meds (ref) | |||
| ≥6 prescription meds | 1.9 | [1.45, 2.47] | 0.0001 |
| Access to healthcare | |||
| Insurance Coverage | |||
| Private (ref) | |||
| Public Insurance | 0.84 | [0.66, 1.08] | 0.1734 |
| Chronic Conditions | |||
| Diabetes | |||
| No (ref) | |||
| Yes | 1.16 | [0.88, 1.53] | 0.2968 |
| Heart Disease | |||
| No (ref) | |||
| Yes | 0.83 | [0.65, 1.07] | 0.1542 |
| High Cholesterol | |||
| No (ref) | |||
| Yes | 0.88 | [0.71, 1.09] | 0.2492 |
| Depression | |||
| No (ref) | |||
| Yes | 2.06 | [1.57, 2.70] | 0.0001 |
| Anxiety | |||
| No (ref) | |||
| Yes | 1.46 | [1.04, 2.05] | 0.0309 |
Note: Based on pooled data from multiple years (N in 2009 = 3450; N in 2010 = 3312; N in 2011 = 3562; N in 2012 = 3881; N in 2013 = 3548; N in 2014 = 3479; and N in 2015 = 3777), who were alive during the calendar year, had health insurance and did not have missing values for the PIA variable.
Abbreviations: ADRD: ref = Reference group, P-values based on survey logistic regression.
Exercise was measured as 3 or more times/week in 2009 and 2010 and 5 or more times/week in 2011 through 2015.