Table 2.

Unadjusted Odds Ratios (UOR) and Adjusted Odds Ratios (AOR) and 95% Confidence Intervals (CI) from Logistic Regressions on Alzheimer’s Disease and related dementiasamong Older adults (≥ 65 years) Medical Expenditures Panel Survey, 2009–2015

Model 1: Unadjusted Model
	UOR	95%CI	P-Value
OA with PIA	2.28	[ 1.68, 3.10]	0.0001
OA without PIA	0.70	[0.47, 1.05]	0.0856
PIA and No OA	2.42	[1.92, 3.04]	0.0001
No PIA and No OA (ref)	1.00	-
Model 2: Adjusted for Biological Factors (Sex, Age, and Race/ethnicity)
	AOR	95%CI
OA with PIA	1.88	[1.39, 2.54]	0.0001
OA without PIA	0.66	[0.44, 0.99]	0.0423
No OA with PIA	1.98	[1.58, 2.49]	0.0001
No PIA and No OA (ref)	1.00	-
Model 3: Fully adjusted model‡
	AOR	95%CI
OA with PIA	1.37	[1.01, 1.86]	0.0408
OA without PIA	0.66	[0.43, 0.99]	0.0460
PIA and No OA	1.44	[1.13, 1.82]	0.0029
No PIA and No OA (ref)	1.00	-

Note: Based on pooled data from multiple years older adults (age ≥ 65 years), who were alive during the calendar year, had health insurance and did not have missing values for PIA

^‡Fully adjusted model controlled for age, sex, race, marital status, poverty status, education, obesity, current smoking, physical activity, polypharmacy, insurance, diabetes, heart disease, high cholesterol, depression, anxiety, region, and calendar year. The fully adjusted model had a c-statistic of 0.81.

Abbreviations: AOR: Adjusted odds ratios; CI: 95% Confidence Intervals; OA: Osteoarthritis; PIA: Pain interference with usual activity;