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. Author manuscript; available in PMC: 2020 Nov 1.
Published in final edited form as: Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Jul 23;1864(11):1669–1680. doi: 10.1016/j.bbalip.2019.07.009

Figure 4.

Figure 4.

Effects of baicalein or knocking-out of 12/15-LO on renal oxidative stress marker TBARs and inflammatory marker MCP-1 excretion levels in LPS injected mice. Baicalein treatment significantly reduced TBARs excretion (A) in LPS injected WT mice. Similarly, knocking-out of 12/15-LO prevented the increase in TBARs excretion in LPS injected 12/15-LO KO mice. The renal inflammatory marker MCP-1 excretion (B) remained significantly higher in LPS injected WT and 12/15-LO mice when compared to control (n=6–8; *P<0.05 vs. control WT group, #P<0.05 vs. WT LPS group and λP<0.05 vs. control LO group).