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. Author manuscript; available in PMC: 2020 Nov 1.
Published in final edited form as: Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Jul 23;1864(11):1669–1680. doi: 10.1016/j.bbalip.2019.07.009

Figure 8.

Figure 8.

Effect of DHA or RvD2 treatment and 12/15-LO knocking-out on creatinine clearance and proteinuria in LPS injected mice. Either DHA or RvD2 treatment increased creatinine clearance and decreased proteinuria in LPS injected WT mice. Although knocking-out of 12/15-LO also decreased creatinine clearance and increased proteinuria in LPS injected 12/15-LO KO mice, these changes were less than LPS injected WT mice and were not further improved with DHA treatment (n=6–8, *P<0.05 vs. control and #P<0.05 vs. LPS group).