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. Author manuscript; available in PMC: 2020 Nov 1.
Published in final edited form as: Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Jul 23;1864(11):1669–1680. doi: 10.1016/j.bbalip.2019.07.009

Figure 9.

Figure 9.

Effects of DHA or RvD2 treatment and 12/15-LO inhibition on urinary excretion levels of TBARs and MCP-1. DHA or RvD2 administration significantly attenuated TBARs and MCP-1 excretion levels in LPS injected WT mice. Knocking-out of 12/15-LO also increased TBARs and MCP-1 excretion in LPS injected 12/15-LO KO mice compared to control 12/15-LO KO mice; however, these changes were not significantly reduced with DHA treatment in LPS injected 12/15-LO KO mice (n=6–8; *P<0.05 vs. control WT or 12/15-LO KO group, #P<0.05 vs. WT LPS group).