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. Author manuscript; available in PMC: 2020 Nov 1.
Published in final edited form as: Biochim Biophys Acta Mol Basis Dis. 2019 Jul 27;1865(11):165516. doi: 10.1016/j.bbadis.2019.07.010

Figure 4. Salubrinal treatment resulted in normalizing the aberrant pro survival & UPR signaling and more mature follicles in GalT- deficient mouse ovaries.

Figure 4.

a) Salubrinal improved the ovulation in GalT-deficient mice (WT=Wild type, KO=GalT−/−) (n=4 for each group). P values are derived from two-way ANOVA followed by Tukey HSD, *the data are significant (p < 0.05).

b) Salubrinal reversed the aberrant Pi3K/Akt and UPR signaling in ovaries from gonadotrophin-stimulated GalT-deficient mouse. Graphical representations on the right (n=4 for each group. P values are derived from Student’s t-test analyses, *p ≤ 0.05, **p ≤ 0.005).