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. Author manuscript; available in PMC: 2020 Mar 16.
Published in final edited form as: Nat Metab. 2019 Sep 16;1(9):899–911. doi: 10.1038/s42255-019-0109-9

Fig. 4. Correlations between mRNA and protein levels.

Fig. 4

a, Proteomaps for visualizing the distributions of the mean mRNA and mean proteins over all FACS gates. Each tile in the map represents a gene, size is proportional to its fraction in the total dataset. Tile colors represent different gene annotations, color-code legend is below the maps. Genes/protein closer on the maps and sharing the same color are closer in function. Visualization was done using https://bionic-vis.biologie.uni-greifswald.de/ 13–15. Color classification key for selected categories is shown at the bottom. b, Gate-averaged mRNA and protein levels are mildly correlated (Spearman’s r=0.5). Shown are three KEGG functional classifications with distinct ratios of mRNAS and proteins. Red is a linear regression line. n = 3,051 genes averaged over 5 mice.