| Duplicates removed | 44 |
| Excluded during initial screening (e.g. press releases; news reports; not relevant drug/indication; preclinical study; reviews; case reports; not randomized trial) | 62 |
| Excluded during writing (e.g. reviews; duplicate data; small patient number; nonrandomized/phase I/II trials) | 23 |
| Cited efficacy/tolerability articles | 5 |
| Cited articles not efficacy/tolerability | 24 |
| Search Strategy: EMBASE, MEDLINE and PubMed from 1946 to present. Clinical trial registries/databases and websites were also searched for relevant data. Key words were trifluridine/tipiracil, Lonsurf, gastric cancer. Records were limited to those in English language. Searches last updated 29 August 2019. | |
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