Fig. 3.

OVA DNTs suppressed cytokine and OVA-specific Ig production. OVA-sensitized mice were treated with an intravenous transfer of OVA DNTs after the first OVA challenge. The mice were challenged daily for the next two days and sacrificed 48 h after the last aerosol challenge. a Inflammatory cytokine-secreting lung CD4⁺ T cells were measured by flow cytometry. b The BALF and serum cytokine levels were assessed by ELISA. c The levels of OVA-specific BALF and serum IgG/IgE were assessed by ELISA. Data are shown as the mean ± SEM; n = 4–5 mice per group. One-way ANOVA was used to calculate significance. *P < 0.05; **P < 0.01. Source data are provided as a source data file