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. 2019 Sep 18;9:13510. doi: 10.1038/s41598-019-49938-9

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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NTP treatment ameliorates HDM-induced AD-like skin inflammation in NC/Nga mice. (a) The experimental scheme for induction of HDM-induced AD-like skin inflammation and NTP treatment. (b) A schematic diagram describing treatment of mice with the NTP- producing machine. (c) NTP treatment inhibited AD-like skin inflammation in NC/Nga mice. (d) H&E staining of mouse back skin (e) NTP treatment reduced epidermal thickness. **P < 0.01, ***P < 0.001. Bar = 400 µm (100×), 100 µm (400×).