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In vivo antitumor activity and safety evaluation. a Tumor volume changes over treatment times. b Tumor volume of five groups: (a) normal saline, (b) free Pp IX (5 mg/kg), (c) Pp IX-loaded HLDM micelles (5 mg/kg of free Pp IX equivalents), (d) free Pp IX (5 mg/kg) plus light irradiation, and (e) Pp IX-loaded HLDM micelles (5 mg/kg of free Pp IX equivalents) plus light irradiation. c The body change of tumor-bearing nude mice
