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. 2019 Sep 12;7:196. doi: 10.3389/fcell.2019.00196

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Copyright © 2019 Ren, Sun, Clinton and Yang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Characterization of APA in chicken embryos. (A) Distribution of the number of poly(A) sites per gene generated during different stages of embryo development. (B) Venn diagram depicting the distribution of poly(A) sites among the 5,004 genes during different stages of embryo development. Each individual cell in the diagram represents the 5,004 genes, and the overlap represents the number of genes that have the same poly(A) sites. (C) Nucleotide composition around poly(A) cleavage sites. (D) The most enriched motif in the 50 bp sequence upstream of the poly(A) tail detected by MEME.