FIGURE 3.

Killing kinetics of the LMM5 and LMM11 against C. albicans. Time-Kill curve of compounds: (A) LMM5 and (B) LMM11. The killing ability of the compounds was plotted from log₁₀ CFU/ml versus time points. Standardized yeast cell suspensions were exposed to Sub-MIC (16 μg/ml), MIC (32 μg/ml) and 2xMIC (64 μg/ml) of LMM5 or LMM11. In time points 0, 2, 4, 6, 8, 12, 24, 28, and 36 h, aliquots were diluted and plated on SDA for CFU/ml determination. Absence of compounds was used as a positive control and the commercial antifungal fluconazole (0.25 μg/ml) was used for comparison. Data are representative of three independent experiments and each data point represents the mean ± standard deviation (error bars).