Table 1.

Effects of carvacrol on random blood glucose and body weight in mice with STZ-induced type 1 diabetes mellitus.

Groups	Random blood glucose (mmol/L)			Body weight (g)
	2 weeks	4 weeks	6 weeks	2 weeks	4 weeks	6 weeks
Con	9.38±0.16	7.81±0.31	8.67±0.94	27.71±0.11	28.67±0.53	30.75±1.11
Con20	9.39±0.44	8.04±0.75	9.16±0.48	27.28±0.19	27.86±0.69	29.71±0.95
T1DM	26.55±1.70**	27.21±0.93**	32.15±1.08**	22.38±0.72**	23.28±0.30**	22.25±0.70**
T1DM+CAR 10	25.48±1.33**	23.52±1.18**	20.70±1.47**#	22.03±0.89**	21.92±0.33**	20.89±0.44**
T1DM+CAR 20	24.04±0.88**	21.07±1.23**#	17.08±1.60**##	21.8±0.74**	21.41±0.39**	21.00±0.47**

Carvacrol was administered once daily after 4 weeks of diabetic induction. Random blood glucose levels and body weight were measured every 2 weeks after carvacrol administration. Con, control mice treated with vehicle (0.1% DMSO); Con20, control mice treated with 20 mg/kg/day of carvacrol; T1DM, STZ induced type 1 diabetic mice with vehicle treatment (0.1% DMSO); T1DM+CAR10, diabetic mice treated with 10 mg/kg/day carvacrol; T1DM+CAR20, diabetic mice treated with 20 mg/kg/day carvacrol. Values are means ± SEM from ten mice in each group. **P<0.01 vs. Con group; ^#P<0.05 vs. T1DM group; ^##P<0.01 vs. T1DM group.