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. 2019 Feb 7;5(5):369–378. doi: 10.1159/000495841

Table 2.

Choroidal nevus with retinal invasion in 8 patients; clinical features at initial evaluation

Total (n = 8 eyes) Stable nevus (n = 6 eyes) Growth of nevus (n = 2 eyes) p value*
Eye 1.00
Right 3 (37) 2 (33) 1 (50)
Left 5 (63) 4 (67) 1 (50)

Best corrected visual acuity (Snellen)
Mean 20/25 20/25 20/25 0.349
Median 20/25 20/25 20/25
20/40 or better 8 (100) 6 (100) 2 (100) 1.00
20/50 or worse 0 (0) 0 (0) 0 (0)

Ocular melanocytosis 3 (37) 2 (33) 1 (50) 1.00
Lens status
Clear 1 (12) 1 (17) 0 (0) 1.00
Cataract 5 (63) 4 (67) 1 (50) 1.00
Intraocular lens 2 (25) 1 (17) 1 (50) 1.00

Nevus meridian
Superior 1 (12) 1 (17) 0 (0) 1.00
Temporal 2 (25) 1 (17) 1 (50) 0.463
Inferior 3 (38) 2 (33) 1 (50) 1.00
Nasal 2 (25) 2 (33) 0 (0) 1.00

Anterior margin of nevus 1.00
Macula 3 (37) 2 (33) 1 (50)
Macula to equator 5 (63) 4 (67) 1 (50)

Posterior margin of nevus
Macula 1 (12) 0 (0) 1 (50) 0.250
Macula to equator 6 (75) 5 (83) 1 (50) 0.463
Equator to ora serrata 1 (12) 1 (17) 0 (0) 1.00
Mean distance to optic nerve (median; range), mm 5 (6; 0–9) 5 (5; 0–9) 6 (6; 5–8) 0.494
Mean distance to fovea (median; range), mm 5 (4; 3–11) 5 (4; 3–11) 4 (4; 3–5) 0.640
Mean largest diameter (median; range), mm 7 (6; 4–10) 7.5 (7.8, 5–10) 4.5 (4.5; 4–5) 0.106
Mean thickness (median; range), mm 2.3 (2.4; 1.4–3.3) 2.5 (2.7; 1.6–3.3) 1.8 (1.8; 1.4–2.2) 0.185
Bruch membrane rupture 8 (100) 6 (100) 2 (100) 1.00
Retinal invasion 8 (100) 6 (100) 2 (100) 1.00
Drusen 4 (50) 4 (67) 0 (0) 0.429
Orange pigment 0 (0) 0 (0) 0 (0) 1.00
Subretinal hemorrhage 1 (12) 1 (17) 0 (0) 1.00
Subretinal fluid 0 (0) 0 (0) 0 (0) 1.00
Fibrous metaplasia of overlying retinal pigment epithelium 2 (25) 2 (33) 0 (0) 1.00

Values are n (%) unless otherwise indicated.

*

Fisher's exact test.

Student's t test.