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. 2019 Feb 7;5(5):369–378. doi: 10.1159/000495841

Table 3.

Choroidal nevus with retinal invasion in 8 patients; imaging findings at initial examination

Total (n = 8 eyes) Stable nevus (n = 6 eyes) Growth of nevus (n = 2 eyes) p value*
Ultrasound features (n = 7)
Configuration
 Dome 7 (100) 5 (100) 2 (100) 1.00
Density
 Hollow 1 (14) 1 (17) 0 (0) 1.00
 Dense 6 (86) 4 (67) 2 (100) 1.00

Optical coherence tomography features (n = 8)
Depth of invasion
 Bruch membrane rupture with outer retinal invasion 5 (63) 3 (50) 2 (100) 0.464
 Bruch membrane rupture with outer and inner retinal invasion 3 (37) 3 (50) 0 (0) 0.464
Drusen
Subretinal fluid
Intraretinal edema
RPE atrophy
RPE hyperplasia
RPE fibrous metaplasia
Choroidal neovascularization
1 (12)
1 (12)
0 (0)
2 (25)
2 (25)
2 (25)
0 (0)
1 (17)
1 (17)
0 (0)
1 (17)
2 (33)
2 (33)
0 (0)
0 (0)
0 (0)
0 (0)
1 (50)
0 (0)
0 (0)
0 (0)
1.00
1.00
1.00
0.463
1.00
1.00
1.00

Fundus autofluorescence features (n = 7)
Hyperautofluorescence 0 (0) 0 (0) 0 (0) 1.00
Hypoautofluorescence 6 (86) 6 (100) 0 (0) 0.035
Mixed hyper- and Hypoautofluorescence 1 (14) 0 (0) 1 (100) 0.143

Fluorescein angiography features (n = 1)
Hypofluorescence 1 (100) 1 (100) na -

Values are n (%). na, not applicable. Italics indicate statistical significance.

*

Fisher's exact test.