Table 2.

Select 24-hour urinary parameters with bardoxolone methyl in the pharmacodynamic study

	Baseline	Day 28	Day 56	Day 84 (off-treatment)
24-hour urinary creatinine, mmol/24 h
N 24	21	15	10
Mean (SD)	11.2 (4.4)	10.8 (4.2) 9.8	8.9 (3.5)	9.0 (2.8)
Median	10.3	9.8	8.9	8.1
24-hour urinary magnesium, mmol/24 h
N 24	19	14	9
Mean (SD)	3.19 (1.73)	2.75 (1.27)	2.93 (1.94)	3.32 (1.63)
Median	2.84	2.70	2.68	3.00
Fractional excretion of magnesium, %
N 24	19	14	9
Mean (SD)	10 (4)	8 (4)	9 (4)	10 (5)
Median	9	8	9	9