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. Author manuscript; available in PMC: 2019 Sep 19.
Published in final edited form as: ACS Chem Biol. 2019 May 24;14(6):1121–1128. doi: 10.1021/acschembio.9b00161

Figure 2.

Figure 2.

(A) Proposed biosynthesis of aspergillicin A and F. Different colors highlight specific domains and peptide modifications. Domains: Cs, starter condensation domain; A, adenylation; PCP, peptidyl carrier protein; C, condensation; E, epimerase; NMeT, N-methyl transferase; TE, thiolesterase. (B) Putative aspergillicin BGC and flanking genes. Synteny analysis identifies that siderophore genes are conserved across different Aspergillus species. In A. arachidicola, the BGC is in two different contigs, indicated by the two brackets.