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. 2019 Sep 19;2019(9):CD000400. doi: 10.1002/14651858.CD000400.pub4

Comparison 5. NSAIDs versus oral progestogens.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Menstrual blood loss (MBL) (mL/cycle) 2 48 Mean Difference (IV, Fixed, 95% CI) ‐22.97 [‐46.57, 0.62]
2 Number of days' bleeding 2 48 Mean Difference (IV, Fixed, 95% CI) ‐0.41 [‐0.95, 0.13]
3 Proportion with non‐adherence 1 32 Peto Odds Ratio (Peto, Fixed, 95% CI) 0.88 [0.05, 14.78]
4 Total adverse events 1 32 Peto Odds Ratio (Peto, Fixed, 95% CI) 0.54 [0.13, 2.26]
5 Adverse events – headache 1 32 Peto Odds Ratio (Peto, Fixed, 95% CI) 0.63 [0.14, 2.86]
6 Adverse events – abdominal pain 1 32 Peto Odds Ratio (Peto, Fixed, 95% CI) 0.86 [0.15, 4.96]
7 Adverse events – nausea 1 32 Peto Odds Ratio (Peto, Fixed, 95% CI) 1.79 [0.17, 18.65]