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. 2019 Sep 19;2019(9):CD000400. doi: 10.1002/14651858.CD000400.pub4

Comparison 8. Mefenamic acid versus naproxen.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Menstrual blood loss (mL/cycle) 2 61 Mean Difference (IV, Fixed, 95% CI) 21.00 [‐5.85, 47.85]
2 Number of days' bleeding 1 35 Mean Difference (IV, Fixed, 95% CI) ‐0.40 [‐1.59, 0.79]
3 Total adverse events 1 35 Peto Odds Ratio (Peto, Fixed, 95% CI) 0.12 [0.01, 2.00]
4 Gastrointestinal adverse events 1 35 Peto Odds Ratio (Peto, Fixed, 95% CI) 0.24 [0.06, 0.87]
5 Central nervous system adverse events 1 35 Peto Odds Ratio (Peto, Fixed, 95% CI) 1.40 [0.34, 5.73]