Cameron 1990.

Methods	Randomisation technique not stated and no blinding MBL over 2 cycles was assessed in 102 women 20 women refused to collect their pads, 10 women had anovulatory cycles and 40 women had MBL < 80 mL/cycle. The remaining 32 women were randomised to treatment arms. No withdrawals or loss to follow‐up, no power calculation made
Participants	Edinburgh, UK 32 women with MBL > 80 mL/cycle, median age 40 years (range 21–51 years) Exclusion criteria: organic disease, anovulatory cycles and non‐compliance with collecting pads
Interventions	Group 1: MFA 500 mg 3 times daily days 1–5 of menses, n = 17 Group 2: norethisterone 5 mg 2 times daily on cycle days 19–26, n = 15 Duration over 2 cycles
Outcomes	MBL (alkaline haematin method) Number of days bleeding Adverse events Patient compliance
Notes	Unclear if ITT analysis was done. Baseline comparability was done. Additional data provided by the author.
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Not stated
Allocation concealment (selection bias)	Unclear risk	Unclear risk
Blinding (performance bias and detection bias) All outcomes	High risk	No blinding
Incomplete outcome data (attrition bias) All outcomes	Low risk	No dropouts reported
Other bias	Low risk	Baseline comparability done