Scenario 1 |
Early disease onset, at age 45 at PND state 1, with a median progression through PND states, and death at age 55 at PND state 4, without severe cardiomyopathy. |
Scenario 2 |
Early disease onset, at age 45 at PND state 1, with a slow progression through PND states, and death at age 65 at PND state 4, without severe cardiomyopathy. |
Scenario 3 |
Late disease onset, at age 60 at PND state 1, with a median progression through PND states, and death at age 70 at PND state 4, without severe cardiomyopathy. |
Scenario 4 |
Late disease onset and late diagnosis, at age 60 during PND state 2, in a patient with severe cardiomyopathy, where the patient dies within 4 years, at PND state 3b, before reaching PND state 4. |