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. 2019 Sep 18;14:220. doi: 10.1186/s13023-019-1199-x

Table 2.

Description of simulated disease scenarios assessed fiscally

Scenario 1 Early disease onset, at age 45 at PND state 1, with a median progression through PND states, and death at age 55 at PND state 4, without severe cardiomyopathy.
Scenario 2 Early disease onset, at age 45 at PND state 1, with a slow progression through PND states, and death at age 65 at PND state 4, without severe cardiomyopathy.
Scenario 3 Late disease onset, at age 60 at PND state 1, with a median progression through PND states, and death at age 70 at PND state 4, without severe cardiomyopathy.
Scenario 4 Late disease onset and late diagnosis, at age 60 during PND state 2, in a patient with severe cardiomyopathy, where the patient dies within 4 years, at PND state 3b, before reaching PND state 4.