Table 3.
The estimated per person economic impact between the ages 40–80 attributed to patients with hATTR amyloidosis in different disease presentation scenarios
| Fiscal Parameters | General Population (Comparator) | Scenario 1 | Scenario 2 | Scenario 3 | Scenario 4 | ||||
|---|---|---|---|---|---|---|---|---|---|
| hATTR Amyloidosis Population | Difference | hATTR Amyloidosis Population | Difference | hATTR Amyloidosis Population | Difference | hATTR Amyloidosis Population | Difference | ||
| Transfer Payments | |||||||||
| Government transfers | € 2150 | € 180,949 | (€ 178,799) | € 285,355 | (€ 283,204) | € 84,011 | (€ 81,861) | € 55,369 | (€ 53,219) |
| Pensions | € 130,082 | € 0 | € 130,082 | € 0 | € 130,082 | € 55,527 | € 74,556 | € 0 | € 130,082 |
| Health costs | € 206,098 | € 269,076 | (€ 62,979) | € 656,129 | (€ 450,031) | € 322,218 | (€ 116,120) | € 110,502 | € 95,596 |
| Total transfers | € 338,330 | € 450,025 | (€ 111,695) | € 941,483 | (€ 603,153) | € 461,756 | (€ 123,426) | € 165,871 | € 172,459 |
| Societal | |||||||||
| Lifetime Earnings | € 577,114 | € 247,559 | € 329,555 | € 348,952 | € 228,162 | € 561,244 | € 15,870 | € 549,494 | € 27,620 |
| Taxation | |||||||||
| Direct tax | € 229,148 | € 100,172 | € 128,976 | € 140,898 | € 88,250 | € 224,631 | € 4517 | € 220,336 | € 8812 |
| Indirect tax | € 90,774 | € 38,939 | € 51,836 | € 54,887 | € 35,888 | € 88,278 | € 2496 | € 86,430 | € 4344 |
| Gross tax | € 319,922 | € 139,111 | € 180,812 | € 195,785 | € 124,138 | € 312,909 | € 7013 | € 306,766 | € 13,156 |
| Outcomes | |||||||||
| Life years lived from age 40 | 36.67 | 15.12 | 21.55 | 24.44 | 12.23 | 28.81 | 7.87 | 24.44 | 12.23 |
| Productive life years lived | 20.15 | 6.60 | 13.55 | 9.77 | 10.39 | 17.89 | 2.26 | 17.34 | 2.82 |