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. 2019 Sep 18;19:931. doi: 10.1186/s12885-019-6143-x

Table 4.

Risk factors for SPCs by univariate and multivariate logistic regression analyses

Variables Univariate Multivariate
OR (95%CI) P value OR (95%CI) P value
Age (≥74 vs < 74) 2.22 (1.37–3.58) 0.005* 1.81 (1.06–3.04) 0.023*
Hypertension (yes vs no) 1.41 (0.83–2.39) 0.21
Diabetes (yes vs no) 1.72 (1.04–2.88) 0.031* 1.29 (0.78–2.19) 0.41
ASA grade (I/II vs III/IV) 0.96 (0.59–1.51) 0.81
Operation time (high vs low) 1.71 (1.03–2.85) 0.029* 1.54 (0.85–2.63) 0.14
Estimated blood loss (high vs low) 0.94 (0.51–1.79) 0.85
Intraoperative fluid utilization (high vs low) 0.92 (0.53–1.58) 0.79
Preoperative CRP (high vs low) 1.83 (1.11–3.08) 0.024* 1.37 (0.79–2.33) 0.25
Preoperative TNF-α (high vs low) 1.15 (0.73–1.77) 0.42
AFR (≤8.49 vs >8.49) 2.54 (1.52–4.22) 0.001* 1.94 (1.09–3.36) 0.017*

The high vs low levels were categorized using the median value as the cut-off value

SPCs Severe postoperative complications, ASA American Society of Anesthesiologists, CRP C-reactive protein, TNF-α Tumor necrosis factor-α, AFR Albumin-to-fibrinogen ratio, OR Odds ratio, CI Confidence interval

*P value< 0.05