Table 1. IC50 Values of Complexes 1–2, Complexes A–B, and Cisplatin toward A549, HeLa, and HepG2 Cancer Cells and Normal Cells.
| IC50 (μM) |
||||
|---|---|---|---|---|
| complex | A549 | HeLa | HepG2 | BEAS-2B |
| [(η5-C5Me4C6H4C6H5)Ir(L1)Cl]PF6 (1) | 23.2 ± 3.6 | 18.7 ± 2.7 | 19.4 ± 7.5 | 19.96 ± 0.7 |
| [(η5-C5Me4C6H4C6H5)Ir(L2)Cl]PF6 (2) | 36.8 ± 1.6 | 28.2 ± 3.8 | 28.7 ± 6.9 | 30.12 ± 0.3 |
| dimer ([(η5-Cpxbiph)IrCl2]2) | >50 | >50 | >50 | >50 |
| complex A | 2.6 ± 0.3 | 3.6 ± 0.8 | 5.5 ± 0.7 | 3.0 ± 0.2 |
| complex B | 4.3 ± 0.2 | 4.2 ± 0.2 | 5.1 ± 0.1 | 7.2 ± 0.6 |
| cisplatin | 21.3 ± 1.7 | 7.5 ± 0.2 | 22.7 ± 1.1 | 42.0 ± 2.3 |