Table 2.
RADA16–I-MA hydrogel release model fitting
| CRADA16-I (mg/mL) |
Model | ||||
|---|---|---|---|---|---|
| Zero–order kinetics | First–order kinetics | Higuchi | Riter–peppas | ||
| 0 | Equation | Mt=1.04k–49.13 | Mt=89.88(1-e-1.21t) | Mt=8.21t1/2+40.32 | Mt=45.43t0.24 |
| R2 | 0.4591 | 0.9773 | 0.6970 | 0.8514 | |
| 5 | Equation | Mt=1.62k–50.75 | Mt=76.22(1-e-1.43t) | Mt=10.58t1/2+34.66 | Mt=52.68t0.19 |
| R2 | 0.2650 | 0.9622 | 0.5792 | 0.6827 | |
| 10 | Equation | Mt=0.84k–55.59 | Mt=92.30(1-e-1.08t) | Mt=8.52t1/2+37.14 | Mt=50.07t0.18 |
| R2 | 0.4024 | 0.9895 | 0.6366 | 0.8129 | |
Abbreviation: R2, determination coefficient; Mt, cumulative release of MA; k, zero-order speed constant.