Fig. 1.

AFR and prognosis in advanced EOC patients. a Predictive value of preoperative AFR for OS in advanced EOC by ROC curve. The cutoff value of AFR in predicting OS was determined to be 7.78 with an AUC of 0.773, 95% CI of 0.710–0.835, a sensitivity of 64.32% and a specificity of 77.78%, respectively (P < 0.001); (b) PFS in advanced EOC patients according to AFR by Kaplan-Meier curve analysis. Patients with a lower preoperative AFR (≤7.78) had a worse PFS than those with a high preoperative AFR (> 7.78) by log-rank test (P < 0.001); (c) OS in advanced EOC patients according to AFR by Kaplan-Meier curve analysis. Patients with a lower preoperative AFR (≤7.78) had a worse OS than those with a high preoperative AFR (> 7.78) by log-rank test (P < 0.001). AFR, albumin-to-fibrinogen ratio; PFS, progression-free survival; OS; overall survival; EOC, epithelial ovarian cancer; ROC, receiver operating characteristic; AUC, the area under the curve; CI, confidence interval