Table 3.
Univariate and multivariate analyses of prognostic factors for overall survival in AML patients
| Whole patients | Univariate | Multivariate | ||||
|---|---|---|---|---|---|---|
| HR (95% CI) | Exp. | P value | HR (95% CI) | Exp. | P value | |
| Flt3-ITD | 0.575–2.330 | 1.158 | 0.681 | 0.885–2.330 | 1.435 | 0.295 |
| NPM1 | 1.044–5.017 | 2.289 | 0.039 | 0.471–3.644 | 1.309 | 0.606 |
| CEBPA | 0.515–2.253 | 1.077 | 0.843 | 0.402–3.666 | 1.215 | 0.730 |
| WBC count | 1.891–4.505 | 2.918 | < 0.001 | 0.804–2.571 | 1.437 | 0.221 |
| Karyotypic classification | 1.628–2.763 | 2.121 | < 0.001 | 1.113–2.188 | 1.561 | 0.010 |
| Foxo3 expression | 0.499–1.156 | 0.762 | 0.210 | 0.341–0.951 | 0.569 | 0.031 |
| Circ-Foxo3 expression | 0.650–1.661 | 1.039 | 0.873 | 0.664–2.200 | 1.208 | 0.536 |
| Age | 2.274–5.538 | 3.549 | < 0.001 | 1.854–5.523 | 3.200 | < 0.001 |