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. 2019 Sep 18;23:321. doi: 10.1186/s13054-019-2601-8

Table 2.

Dynamic changes of biological and echocardiographic data during the second spontaneous breathing trial

Biological and echocardiographic data Before At the end p
Success (n = 76)
Troponin T, ng/l 297 (926) 303 (969) 0.641
NT-proBNP, ng/l 4166 (7316) 3975 (6632) 0.159
Protein, g/l 59.1 (10.9) 60.4 (10.1) 0.040
E mitral wave, cm/s 87.4 (24.4) 89.9 (26.7) 0.248
E/A ratio 0.99 (0.39) 1.00 (0.52) 0.736
E/e’ ratio 10.6 (5.7) 10.7 (5.4) 0.778
LVEF, % 52 (15) 53 (14) 0.323
CO, l/min 5.9 (1.8) 6.2 (2.0) 0.225
Failure (n = 132)
Troponin T, ng/l 410 (1866) 418 (1921) 0.326
NT-proBNP, ng/l 5726 (14509) 5983 (15476) 0.015
Protein, g/l 59.8 (9.1) 62.0 (9.0) < 0.001
E mitral wave, cm/s 88.6 (33.7) 101.9 (36.0) < 0.001
E/A ratio 1.04 (0.54) 1.18 (0.61) 0.003
E/e’ ratio 11.1 (6.7) 11.8 (6.9) 0.040
LVEF, % 54 (14) 55 (15) 0.048
CO, l/min 5.7 (2.0) 6.1 (2.2) 0.012

NT-proBNP amino terminal pro-brain natriuretic peptide, E early diastolic wave velocity, A late diastolic wave velocity, e’ tissue Doppler early wave velocity at the lateral mitral valve annulus, LVEF left ventricle ejection fraction, CO cardiac output

Data are expressed as mean (standard deviation). p values were calculated using paired Student’s t test