Table 4.

Prevalence of weaning-induced cardiac pulmonary edema (WiPO) in patients with weaning-induced cardiac ischemia (WiCI) during the second spontaneous breathing trial

WiCI	WiPO (liberal definition)		p	WiPO (conservative definition)		p
	No (n = 73)	Yes (n = 104)		No (n = 141)	Yes (n = 36)
ESC 2012	11 (15.1)	25 (24.0)	0.144	26 (18.4)	10 (27.8)	0.214
AHA 2013	6 (8.2)	6 (5.8)	0.555	11 (7.8)	1 (2.8)	0.464

WiPO weaning-induced cardiac pulmonary edema, WiCI weaning-induced cardiac ischemia, ESC European Society of Cardiology, AHA American Heart Association

Data are expressed as number of patients (percentage)

WiPO was defined as follows: conservative definition (at least two positive criteria) and liberal definition (at least one positive criterion). Criteria used for WiPO were as follows: (i) echocardiographic findings at the end of the SBT: E/A ratio > 0.95 and E/e’ ratio > 8.5; (ii) increase of BNP (≥ 48 ng/l) or NT-proBNP (≥ 21 ng/l) levels during the SBT; (iii) increase of protein level (> 6%) during the SBT. WiCI was defined as follows: (i) ESC 2012: ST elevation in two contiguous leads (≥ 0.10 mV in all leads other than V₂–V₃; ≥ 0.20 mV in V₂–V₃ in men ≥ 40 years; ≥ 0.25 mV in V₂–V₃ in men < 40 years; ≥ 0.15 mV in V₂–V₃ in women), or ST depression ≥ 0.05 mV in two contiguous leads; (ii) AHA 2013: ST elevation or depression ≥ 0.10 mV in two contiguous leads