Skip to main content
. 2019 Sep 18;20:718. doi: 10.1186/s12864-019-6063-9

Table 1.

The expression of 20 novel candidate transcription factors in cerebellar development (bolded genes are those examined with qRT-PCR and in utero knock-down). Five genes well known in cerebellar development with their expression levels for comparison are shown at the bottom of the table, in italics

Refseq Gene symbol Mean Max KO phenotype Eur-express Allen Brain
NM_010496 Id2 341 529 postnatal lethality Y
NM_057172 Fubp1 252 469 NO KO
NM_011865 Pcbp1 212 365 NO KO Y
NM_016889 Insm1 74 183 perinatal and neonatal lethality Y
NM_001160410 Scrt2 80 180 NO KO Y
NM_001008542 Mxi1 90 168 progressive hyperplasia in the spleen and prostate Y
NM_009716 Atf4 117 167 postnatal lethality Y
NM_130893 Scrt1 76 161 NO KO
NM_001103165 Pcbp2 90 147 NO KO
NM_001024918 Rfx4 52 138

missing dorsal-mid line structure of the cortex,

neonatal lethality

Y
NM_009628 Adnp 100 132 embryonic death between E8.5 and E9
NM_010772 Maz 101 128 NO KO Y
NM_011265 Rfx3 77 127 embryonic and perinatal lethality, Y
NM_181322 Ctcf 86 120 die prior to E9.5
NM_013780 Npas3 56 114 exhibit abnormal behavior and nervous system morphology Y
NM_001085492 Rere 65 88

embryonic lethality with abnormalities

in neural tube development

NM_011732 Ybx1 60 86 embryonic and perinatal lethality
NM_001093776 Myt1l 49 85 NO KO Y
NM_023739 Nfx1 74 84 NO KO
NM_015753 Zeb2 41 83 embryonic death between embryonic days 9.5 and 10.5 Y
Expression of genes known to cerebellar development
NM_010894 Neurod1 299 1035
NM_009573 Zic1 216 408
NM_001244200 Pax6 58 107
NM_001289916 Rora 35 59
NM_007500 Atoh1 28 58