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. 2018 Jan;23(1):66–70. doi: 10.17712/nsj.2018.1.20170209

Table 2.

The demographic data and characteristics of comorbid MFS and MG (5 cases).

characteristics Case 1 Case 2 Case 3 Case 4 Case 5
Author (yr) Mak W(2005) Silverstein MP(2008) Lau KK(2009) Tanaka Y(2016) Our case
Population Hong Kong/China USA Hong Kong/China Japan China
Gender M M F F M
Age 40 43 84 69 72
Preceding factors + - + - -
Clinical characteristics Limb weakness, areflexia, ptosis, ophthalmoplegia Ataxia, areflexia, ophthalmoplegia, ptosis weakness, areflexia, ptosis, ophthalmoplegia, dysphagia, dysarthria, respiratory failure Acute bilateral ptosis, ophthalmoplegia, ataxic gait, and areflexia Acute bilateral ptosis, ophthalmoplegia, diplopia
Albumino-cytologic dissociation + - + - +
Nerve conduction + - + - +
RNS - + + + +
Anti-AChR antibody + + + + +
Anti-GQ1b antibody + - - + +
Edrophonium chloride
Treatment plasmapheresis, pyridostigmine - Pyridostigmine, IVIG IVIG, Steroid pyridostigmine, IVIG
Thymectomy - - - - +
Prognosis 1 0 0 1 0

M- Male, F - Female, MG - Myasthenia gravis, MFS - Miller Fisher Syndrome, IVIG - intravenous immunoglobulin, RNS - repetitive nerve stimulation, Functional outcome was ranked according to the adopted scale by Hughes: 0, healthy; 1, minor symptoms or signs, able to run; 2, able to walk >5 m without assistance, but unable to run; 3, able to walk >5 m with assistance; 4, bed- or chair-bound; 5, requiring assisted ventilation for at least part of the day; and 6, dead. “+” indicates the patient had precipitating factors from infectious disease.”-” indicates the patient did not have precipitating factors from infectious disease. As for the other parameters, “+” indicates positive findings, and “-” indicates negative findings