Table 1.

ENSMBL genes significantly influenced by density (low vs. high), aggression intensity (number of agonistic interaction), skin brightness or their interactions among the six most aggressive and six least aggressive fish at each density

Gene ID	log2 fold change	SE	stat	padj	Gene name	Gene description	GOTerm (BP)
Aggressive fish
Influenced by density (n = 8)
ENSONIG00000009137	−32.47	6.21	−5.23	0.00	krt5	keratin 5
ENSONIG00000001057	−11.64	2.70	−4.31	0.03	sst1.1	somatostatin 1, tandem duplicate 1	0010469
ENSONIG00000002652	−9.19	2.17	−4.23	0.04	jarid2b	jumonji, AT‐rich interactive domain 2b	0006355;0007275;0016569;0031061 0051574
ENSONIG00000010340	8.47	1.92	4.40	0.03	arhgef1a	Rho guanine nucleotide exchange factor (GEF) 1a	0035556;0035023
ENSONIG00000003670	14.19	2.58	5.50	0.00	nnt	nicotinamide nucleotide transhydrogenase	0015992;0055114
ENSONIG00000019114	19.53	4.51	4.33	0.03	MFAP4 (one of many)	Microfibril‐associated protein 4
ENSONIG00000020827	25.72	5.67	4.54	0.02	_	_
ENSONIG00000015953	35.47	4.91	7.22	0.00	bag6l
Influenced by number of attacks (n = 2)
ENSONIG00000000379	0.13	0.03	4.58	0.04	minpp1a	multiple inositol‐polyphosphate phosphatase 1a
ENSONIG00000015953	0.41	0.06	6.67	0.00	bag6l	BCL2‐associated athanogene 6 like
Influenced by brightness (n = 1)
ENSONIG00000015953	38.16	5.95	6.41	0.00	bag6l	BCL2‐associated athanogene 6, like
Influenced by density × no. of attacks (n = 19)
ENSONIG00000003670	0.08	0.01	7.17	0.00	Nnt	nicotinamide nucleotide transhydrogenase	0015992;0055114
ENSONIG00000004830	−0.09	0.02	−4.11	0.04	si:ch73‐335l21.4	si:ch73‐335l21.4
ENSONIG00000006273	−0.05	0.01	−5.01	0.00	tuft1a	tuftelin 1a
ENSONIG00000006744	−0.15	0.03	−5.61	0.00	zgc:162944	zgc:162944
ENSONIG00000006747	−0.15	0.03	−5.68	0.00	irg1	immunoresponsive 1 homolog (mouse)	0006954;0002376;0045087
ENSONIG00000007532	−0.06	0.01	−5.45	0.00	zgc:122979	zgc:122979	0006457
ENSONIG00000009137	−0.15	0.03	−4.86	0.00	krt5	keratin 5
ENSONIG00000009460	−0.16	0.04	−4.09	0.04	_	_
ENSONIG00000009551	−0.06	0.01	−4.10	0.04	SPIDR	scaffolding protein involved in DNA repair	0000724;0006974
ENSONIG00000010366	−0.05	0.01	−4.89	0.00	Txnipa	thioredoxin‐interacting protein a
ENSONIG00000012279	−0.11	0.03	−4.18	0.03	zmp:0000000801	zmp:0000000801	0007186
ENSONIG00000015140	−0.13	0.03	−4.85	0.00	_	_
ENSONIG00000015264	−0.06	0.01	−4.49	0.01	Fosab	v‐fos FBJ murine osteosarcoma viral oncogene homolog Ab	0033555;0006355
ENSONIG00000015953	0.13	0.02	6.50	0.00	bag6l	BCL2‐associated athanogene 6, like
ENSONIG00000016087	−0.06	0.01	−5.62	0.00	ddit4	DNA‐damage‐inducible transcript 4	0009968
ENSONIG00000016884	−0.05	0.01	−4.98	0.00	nt5dc2	5′‐nucleotidase domain containing 2
ENSONIG00000018737	0.05	0.01	4.05	0.05	Pomca	proopiomelanocortin a	0007218;0032400;0033555
ENSONIG00000019777	−0.09	0.02	−4.21	0.03	hbae5	haemoglobin, alpha embryonic 5	0015671
ENSONIG00000021429	−0.08	0.02	−4.62	0.01	Cebpd	CCAAT/enhancer‐binding protein (C/EBP), delta	0006355
Influenced by density × brightness (n = 3)
ENSONIG00000003670	19.59	3.48	5.63	0.00	Nnt	nicotinamide nucleotide transhydrogenase	0015992;0055114
ENSONIG00000010340	12.50	2.59	4.83	0.01	arhgef1a	Rho guanine nucleotide exchange factor (GEF) 1a	0035556;0035023
ENSONIG00000015953	35.63	6.16	5.78	0.00	bag6l	BCL2‐associated athanogene 6, like
Influenced by no. of attacks × brightness (n = 5)
ENSONIG00000006744	0.69	0.14	4.78	0.01	zgc:162944	zgc:162944
ENSONIG00000006747	0.70	0.14	4.85	0.01	irg1	immunoresponsive 1 homolog (mouse)	0006954;0002376;0045087
ENSONIG00000009137	0.69	0.15	4.45	0.03	krt5	keratin 5
ENSONIG00000015140	0.71	0.14	4.93	0.01	_	_
ENSONIG00000015953	−0.76	0.11	−6.84	0.00	bag6l	BCL2‐associated athanogene 6, like
Nonaggressive fish
Influenced by density (n = 3)
ENSONIG00000006467	−24.58	3.94	−6.25	0.00
ENSONIG00000006469	−27.49	5.91	−4.65	0.02	prl	prolactin	0010469
ENSONIG00000015264	7.48	1.56	4.80	0.01	fosab	v‐fos FBJ murine osteosarcoma viral oncogene homolog Ab	0033555;0006355
Influenced by brightness (n = 38)
ENSONIG00000002382	−37.14	9.17	−4.05	0.04	_	_
ENSONIG00000015235	−24.84	3.79	−6.55	0.00	oxt	oxytocin	0050801
ENSONIG00000015218	−18.10	4.39	−4.12	0.03	avp	arginine vasopressin	0007165;0010469
ENSONIG00000003962	−17.98	3.15	−5.70	0.00	_	_
ENSONIG00000002871	−16.93	3.24	−5.23	0.00	prdm12b	PR domain containing 12b	0006351;0006355; 0021521
ENSONIG00000007689	−13.67	2.75	−4.97	0.00	grp	gastrin‐releasing peptide(grp)	0007218
ENSONIG00000020662	−12.86	2.94	−4.37	0.01	_	_
ENSONIG00000005071	−12.73	2.92	−4.37	0.01	_	_
ENSONIG00000002896	−12.49	3.13	−3.99	0.04	sp8b	sp8 transcription factor b	0006351;0006355;0030326
ENSONIG00000005998	−12.16	3.08	−3.95	0.04	sytl3	synaptotagmin‐like 3	0006886;0006887; 0006906
ENSONIG00000004333	−10.17	1.93	−5.27	0.00	_	_
ENSONIG00000001128	−9.62	1.96	−4.91	0.00	hcrt	hypocretin (orexin) neuropeptide precursor	0007218;0007631;0033555
ENSONIG00000009224	−9.23	1.88	−4.91	0.00	_	_
ENSONIG00000010719	−8.92	2.23	−4.00	0.04	si:ch211‐236k19.2	si:ch211‐236k19.2	0006355
ENSONIG00000004631	−8.80	2.11	−4.18	0.03	col8a2	collagen, type VIII, alpha 2
ENSONIG00000014386	−7.94	1.46	−5.44	0.00	arxa	aristaless‐related homeobox a	0003322;0006351;0006355
ENSONIG00000019324	−7.58	1.91	−3.96	0.04	tprg1	tumour protein p63 regulated 1
ENSONIG00000003653	−7.40	1.53	−4.84	0.00	_	_
ENSONIG00000001403	−7.31	1.86	−3.93	0.04	meis2a	Meis homeobox 2a	0006355;0048703;
ENSONIG00000003843	−5.75	1.08	−5.31	0.00	nts	neurotensin	0010469
ENSONIG00000017229	−4.67	1.18	−3.95	0.04	trh	thyrotropin‐releasing hormone	0001692;0007165;0009755
ENSONIG00000014561	−4.50	1.01	−4.48	0.01	tacr3a	neuromedin‐K receptor‐like	0007165;0007186
ENSONIG00000019723	−4.20	1.04	−4.05	0.04	s100a10a	S100 calcium‐binding protein A10a	0042127
ENSONIG00000009148	−3.64	0.86	−4.22	0.02	vax1	ventral anterior homeobox 1	0006351;0006355;0007275
ENSONIG00000016412	−2.88	0.65	−4.45	0.01	_	_
ENSONIG00000007099	−2.73	0.66	−4.13	0.03	_	_
ENSONIG00000014947	−2.68	0.67	−3.99	0.04	CACNA2D1	calcium voltage‐gated channel auxiliary subunit alpha2delta 1	1904646;0070588
ENSONIG00000016069	−2.59	0.52	−5.02	0.00	_	_
ENSONIG00000008322	−2.58	0.64	−4.05	0.04	dhrs13a.3	dehydrogenase/reductase (SDR family) member 13a, duplicate 3
ENSONIG00000000606	2.10	0.54	3.86	0.05	eif4a1a	eukaryotic translation initiation factor 4A1A	0006412;0006446;0016926
ENSONIG00000014333	2.27	0.56	4.03	0.04	syn2b	synapsin IIb	0007269
ENSONIG00000006168	2.69	0.67	3.99	0.04	_	_
ENSONIG00000010283	3.36	0.77	4.39	0.01
ENSONIG00000016676	4.54	1.14	3.98	0.04
ENSONIG00000009325	4.69	1.20	3.91	0.05	CYR61	cysteine‐rich angiogenic inducer 61	0001558;0007155;0007165; 0007267;0060548
Influenced by density × brightness (n = 1)
ENSONIG00000006467	−38.04	6.79	−5.60	0.00	_	_

Positive log2 fold change values denote downregulation at high density (HD) compared to low density (LD), while for continuous predictors they represent rate of unit change.