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. 2018 Oct 16;21(6):1345–1354. doi: 10.1038/s41436-018-0337-5

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — Pipeline for extracting pharmacogenetically relevant alleles from existing genotyping data. Panel (a) depicts the different data sets, their overlap (Venn diagram), and how the data were processed. Panel (b) zooms into the detection of star alleles according to specific definition tables. ES exome sequencing, GS genome sequencing, GSA Global Screening Array, OMNI HumanOmniExpress.