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. 2019 Sep;5(3):320–331. doi: 10.18383/j.tom.2019.00012

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© 2019 The Authors. Published by Grapho Publications, LLC

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Figure 5. — Representative PDX T2-weighted (T2W) images and magnetic resonance (MR) parametric maps. T2W (A), T2W-FatSat (B), T1 (C), T2 (D), ADC (E), and DCE-AUC (F) parametric maps from a single central slice through a 206-μL tumor. T2W image intensity scaling is arbitrary. Parametric map intensities are given by vertical scale bars. The tumor is outlined with a yellow line. Isolated white or black voxels (specks) generally occur in anatomic regions of very low signal-to-noise ratio (SNR) under the protocol conditions and thus reflect a modeling (parameter estimation) failure. The hyperintense T2W fat signal is a known artifact of the fast spin-echo (FSE) protocol (45–47).