Fig. 1.

Facial appearance of patients with haploinsufficiency of USP7. While most individuals have facial dysmorphisms, including deep-set eyes and a prominent nasal septum, extending below the alae nasi, the dysmorphic features present across a varied spectrum and do not represent a recognizable dysmorphic condition at this time. (a) Patient 3. (b) Patient 7. (c) Patient 8. (d) Patient 10. (e) Patient 11. (f) Patient 13. (g) Patient 14. (h) Patient 15. (i) Patient 16. (j) Patient 17. (k) Patient 18. (l) Patient 19. (m) Patient 21. (n) Patient 22.