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Cytokine levels in chamber fluids on Day 4: (A) IL-1β; (B) IL-6. Cytokine levels in chamber fluids for negative control and treatments with 37.5 mg/kg HP-PO/NO polymers as a function of time: (C) IL-1β; (D) IL-6. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p <0.0001 compared to untreated negative control.
