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Sprague Dawley rat, thymus, cortex. Apoptosis, lymphocyte and necrosis, lymphocyte. Mouse was given cyclophosphamide. Because of the overwhelming apoptosis, there was caspase depletion and the apoptotic phenotype eventually became necrosis. Apoptosis and necrosis may be diagnosed separately or may be diagnosed together as a single entity (apoptosis/necrosis or apoptosis/single cell necrosis).
