Table 4:

Compartments and cellular components of the spleen

Compartment	Components
Periarteriolar lymphoid sheath	Dominant T lymphocyte area
	- T lymphocytes
	- B lymphocytes
	- Fibroblastic reticular cells (FRCs)
	- Interdigitating dendritic cells
Follicle	Dominant B lymphocyte area
	- B lymphocytes
	- Follicular dendritic cells (FDCs)
Germinal center	Dominant B lymphocyte area
	- B lymphocytes in several stages of development and maturation
	- T lymphocytes
	- Follicular dendritic cells (FDCs)
	- Tingible body macrophages
Marginal Zones	- Marginal zone B cells
	- Marginal zone macrophages (MZMs)
	- Marginal metallophilic macrophages (MMMs)
	- Fibroblastic reticular cells (FRCs)
	- T lymphocytes
Red pulp	- Red pulp macrophages
	- Red blood cells
	- Hematopoietic cells
	- Lymphocytes
	- Plasma cells
	- Fibroblastic reticular cells (FRCs)