Table 5:
Compartments and cellular components of lymph nodes
Compartment | Components |
---|---|
Follicle | Dominant B lymphocyte area |
- Primary follicles contain small resting naive B cells | |
- Follicular dendritic cells (FDCs) | |
Germinal center | - B lymphocytes in several stages of development and maturation |
- T lymphocytes | |
- Follicular dendritic cells (FDCs) | |
- Tingible body macrophages | |
Interfollicular cortex Paracortex | Dominant T lymphocyte areas |
- T lymphocytes | |
- B lymphocytes | |
- Fibroblastic reticular cells (FRCs) | |
- Interdigitating dendritic cells | |
- High endothelial venules (HEV) | |
Medullary cords | - Lymphocytes |
- Plasma cells | |
- Fibroplastic reticular cells (FRCs) | |
- Macrophages | |
Sinuses (subcapsular, transverse, paracortical, medullary) | - Macrophages |
- Fibroblastic reticular cells (FRCs) |