Table 6:

Compartments and cellular components of MALT^*

Compartment	Components
Follicle-associated epithelium (FAE)	- Microfold (M) epithelial cells within the epithelium (scarcity or absence of goblet cells)
	- (dendrites of) Dendritic cells
	- Macrophages
	- Lymphocytes
Subepithelial dome (SED) Syn. Dome	- Dendritic cells
	- Macrophages
	- T lymphocytes
	- Reticular cells
Follicle	- Dominant B lymphocyte area
	- Primary follicles contain small resting virgin B cells
	- Follicular dendritic cells (FDCs)
Mantle	- Small resting B cells like in primary follicle
Germinal center	- B lymphocytes in several stages of development and maturation
	- T lymphocytes
	- Follicular dendritic cells (FDCs)
	- Tingible body macrophages
Interfollicular area Syn. Parafollicular area	- Dominant T lymphocyte area
	- T lymphocytes
	- B lymphocytes
	- Fibroblastic reticular cells (FRCs)
	- Dendritic cells
	- High endothelial venules (HEV)

^*Adapted from Kuper et al. 2017. Compartmentalization is based on Peyer’s patches and NALT. Isolated lymphoid follicles (ILFs) and cryptopatches do not show such degree of organization.¹⁴⁰