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(A, C and E) The cells were treated with different concentrations of memantine (10–800 μM), incubated for 24, 48 and 72 hours. (B, D and F) IC50 values were obtained from a nonlinear regression curve; the determined IC50 values were 580 ± 22 μM, 279 ± 2 μM and 257 ± 4.7 μM, respectively. Comparison among the groups treated and not treated with memantine (p <0.05). Data are expressed as a percentage ± standard deviation.
