Fig 5. Sensorimotor connectivity of structural and functional seeds during sequential learning.

(A) Negative connectivity with the left SMC was generated from three structural seeds (A2, B1, and B2) and a functional seed selected from each motor task; positive connectivity with the right SMC was generated from an anterior functional seed (left column, memseed+). Connectivity from the left hippocampus was more prevalent than from the right (right column). (B) Beta values for connectivity (left) and the total number of SMC voxels with significant connectivity generated from seeds in each hemisphere (right) indicate a role for both the left and right hippocampus. Connectivity from global analysis of both could be greater than connectivity from the left or right hippocampus by itself.